What Is Prolozone Therapy and How Does It Work?
Chronic pain affects millions of Americans each year, and for many, traditional solutions like painkillers, surgery, or corticosteroid injections are either ineffective or come with undesirable side effects. That’s where Prolozone therapy comes in—an innovative, non-surgical treatment that harnesses the power of oxygen and natural healing compounds to address the root cause of pain and inflammation.
In this blog, we’ll explore exactly what Prolozone therapy is, how it works, what conditions it treats, and why Divine Health Miami, led by Dr. Francisco Miranda, is one of the top integrative clinics in Miami, Florida, to receive this regenerative pain relief treatment.
Table of Contents
- What Is Prolozone Therapy? 
- How Does Prolozone Therapy Work? 
- What’s in a Prolozone Injection? 
- What Conditions Can Prolozone Therapy Help With? 
- Is Prolozone Therapy Safe and Effective? 
- Prolozone vs PRP: Which Is Better? 
- What to Expect During and After Treatment 
- Is Prolozone Covered by Insurance? 
- Why Choose Divine Health Miami for Prolozone? 
- FAQs About Prolozone Therapy 
- Conclusion: Natural Healing Starts at Divine Health Miami 
What Is Prolozone Therapy?
Prolozone therapy is a form of regenerative injection therapy that combines ozone (O3) with vitamins, minerals, and homeopathic anti-inflammatory medications. The term “Prolozone” is derived from “proliferation” and “ozone,” highlighting its purpose: to regenerate and repair damaged tissues by stimulating the body’s natural healing response.
Unlike steroid injections, which merely mask pain, Prolozone therapy works by improving oxygenation, increasing circulation, and accelerating tissue repair in joints, tendons, ligaments, and soft tissues.
It’s commonly used as a treatment for:
- Joint pain (knees, hips, shoulders) 
- Back pain and herniated discs 
- Arthritis and osteoarthritis 
- Sciatica and nerve inflammation 
- Tendonitis 
- Fibromyalgia 
How Does Prolozone Therapy Work?
Prolozone injections work on the principle that oxygen is essential for healing. Damaged tissues often suffer from poor oxygenation, which leads to pain, degeneration, and chronic inflammation. Ozone—a highly active form of oxygen—stimulates tissue regeneration and boosts antioxidant defenses.
Here’s a breakdown of the three-part process:
- Injection of Anti-Inflammatory Solution – This includes vitamins, minerals, and homeopathic agents that reduce inflammation and nourish the tissue. 
- Prolotherapy Stimulus – A mild proliferative agent may be used to trigger the body’s healing response. 
- Ozone Gas Injection – Medical-grade ozone is injected directly into the affected area to promote rapid healing by increasing oxygenation and circulation. 
This process not only helps reduce pain but can restore joint stability, improve mobility, and even reverse some of the degenerative processes that cause chronic conditions.
What’s in a Prolozone Injection?
A typical Prolozone injection may include:
- Vitamin B-complex – Helps cellular repair 
- Homeopathic remedies – Anti-inflammatories and pain relievers 
- Minerals like magnesium and zinc – Support tissue regeneration 
- Medical ozone (O3) – The key regenerative component 
Each blend is customized based on the patient's condition and health history, which is why treatment at a skilled clinic like Divine Health Miami is essential.
What Conditions Can Prolozone Therapy Help With?
Prolozone is remarkably versatile. It’s most commonly used for:
Joint and Musculoskeletal Pain
- Osteoarthritis (knee, hip, shoulder, spine) 
- Meniscus injuries 
- Rotator cuff tears 
Spine and Back Pain
- Herniated discs 
- Sciatica 
- Chronic lower back pain 
Soft Tissue and Inflammatory Conditions
- Tendonitis (e.g., tennis elbow, Achilles) 
- Plantar fasciitis 
- Fibromyalgia 
Neuropathic Pain
- Trigeminal neuralgia 
- Carpal tunnel syndrome 
Many patients seek out Prolozone when traditional treatments have failed or when they want to avoid surgery and pharmaceutical dependency.
Is Prolozone Therapy Safe and Effective?
Safety:
Prolozone therapy is extremely safe when administered by a trained medical provider. Ozone therapy has been used for decades in Europe and is growing in popularity in the United States for its effectiveness and low risk.
Side effects are rare and usually limited to temporary soreness at the injection site.
Effectiveness:
While results vary, most patients report significant pain relief and improved mobility after just 1–3 sessions. Chronic conditions may require 4–6 treatments for optimal results.
Studies and anecdotal evidence suggest that Prolozone works not only for pain relief but also as a true healing therapy, addressing the root of inflammation rather than covering symptoms.
Prolozone vs PRP: Which Is Better?
Both Prolozone and Platelet-Rich Plasma (PRP) are regenerative therapies, but they differ in approach:
Feature
- Prolozone 
- PRP 
Core Ingredient:
- Ozone + nutrients 
- Platelets from patient’s blood 
Speed of Results
- Often noticeable after 1-2 sessions 
- Typically slower onset 
Anti-inflammatory effect
- Immediate 
- Delayed, as inflammation must peak 
Common Uses
- Joints, spine, soft tissue injuries 
- Tendon/ligament injuries, arthritis 
Prolozone may be ideal for patients who want a less invasive, lower-cost, and quick-acting alternative to PRP.
What to Expect During and After Treatment
At Divine Health Miami, your experience includes:
- Initial Consultation with Dr. Francisco Miranda 
- Customized Treatment Plan based on your condition and medical history 
- In-Office Injections done in a calm, professional environment 
Most sessions take less than 30 minutes. Aftercare may involve rest, hydration, and light movement.
Results can be felt within days and often improve with each session.
Is Prolozone Covered by Insurance?
Most insurance plans do not currently cover Prolozone therapy, as it is considered an alternative or integrative treatment. However, Divine Health Miami offers transparent pricing and flexible payment options to make this natural therapy more accessible.
Why Choose Divine Health Miami for Prolozone?
If you’re searching for Prolozone therapy in Miami, Kendall, Coral Gables, Doral, Hialeah, Aventura, or South Florida, look no further than Divine Health Miami.
Why patients trust Divine Health Miami:
- Led by Dr. Francisco Miranda, with over 20 years of clinical experience in integrative and functional medicine 
- Known for a whole-person approach that treats root causes, not just symptoms 
- Offers a full suite of services: primary care, anti-aging, IV therapy, regenerative injections, and more 
- Compassionate care team dedicated to helping you heal naturally and fully 
At Divine Health, you’re not just a patient—you’re part of a healing journey guided by faith, science, and holistic wisdom.
FAQs About Prolozone Therapy
Q: Are Prolozone injections painful?
 A: Mild discomfort is possible, but a numbing agent is used to minimize pain.
Q: How many sessions do I need?
 A: Many patients feel relief after 1–2 sessions, but chronic issues may need 4–6.
Q: How long do results last?
 A: Results can last months or even years depending on lifestyle and the condition treated.
Q: Can I return to work or exercise after treatment?
 A: Most patients return to normal activity the same day.
Q: Is Prolozone safe for seniors?
 A: Yes, it is especially effective for age-related joint degeneration and arthritis.
Conclusion: Natural Healing Starts at Divine Health Miami
Pain doesn’t have to define your life. Whether you're struggling with knee arthritis, chronic back pain, or stubborn tendonitis, Prolozone therapy offers a non-surgical, drug-free path to healing.
At Divine Health Miami, Dr. Francisco Miranda and his team offer personalized, integrative solutions that go beyond symptom relief. From your first consultation to your final follow-up, you'll be treated with care, respect, and the confidence that your body can heal.
Ready to experience the power of Prolozone?
 Schedule your consultation with Divine Health Miami today. Serving Miami, Kendall, Doral, Coral Gables, Hialeah, Aventura, and all of South Florida, we're here to help you reclaim your mobility, vitality, and joy.
👉 Visit Divine Health Miami to learn more or book an appointment today.
